Tuesday, July 26, 2011

Que

A 32-year-old man has had worsening headaches for the past 2 months. On physical examination he is afebrile. He has no lymphadenopathy or hepatosplenomegaly. A head CT scan reveals a 3 cm mass lesion to the right of midline next to the lateral ventricle. A stereotaxic brain biopsy is performed and microscopic examination shows diffuse large B cell lymphoma. A bone marrow biopsy is performed and on microscopic examination shows slightly decreased cellularity of all cell lines. Which of the following laboratory test findings is this patient most likely to have?

 A Elevated terminal deoxyribonucleodidyl transferase
 B Bence-Jones proteinuria
 C Elevated serum IgM
 D HIV-1 RNA of 8000 copies/mL
 E Lymphoma positive for tartrate-resistant acid phosphatase

Answer is C. Elevated serum IgM.

  E. is hairy cell leukemia
 B. Is multiple Myeloma
 A. is ALL
 D. Primary CNS lymphoma

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